Time to Live Forever

 http://web.mit.edu/newsoffice/2011/antiviral-0810.html

Leave it to the genius collective at MIT to develop a potential cure for the common cold, and flu, and other viruses that seem immune to any and all real medications we have currently.  I'm no expert in molecular biology, or any type of biology for that matter, but this quote from the article was my exact question when i read the headline, how are they going to keep the drug from becoming ineffective due to the evolution of numerous viruses that it's supposed to fight.

"Rider had the idea to combine a dsRNA-binding protein with another protein that induces cells to undergo apoptosis (programmed cell suicide) — launched, for example, when a cell determines it is en route to becoming cancerous. Therefore, when one end of the DRACO binds to dsRNA, it signals the other end of the DRACO to initiate cell suicide.
Combining those two elements is a “great idea” and a very novel approach, says Karla Kirkegaard, professor of microbiology and immunology at Stanford University. “Viruses are pretty good at developing resistance to things we try against them, but in this case, it’s hard to think of a simple pathway to drug resistance,” she says."


 True genius, just make the antivirus kill the entire process of transcription and you don't have to worry about the active site of the protein adapting to your inhibitor like in antibiotics.  At least i think that's how it works from a basic Biology class years ago.  If you're interested it's an interesting article and not too bloated at all with scientific mumbo jumbo. 

I'm making bacon wrapped eggs sometime this week for breakfast so stay tuned, and if you have any eggcellent suggestions(see what i did there...) let me know and i'll try to incorporate them into a future post. 

3 comments:

  1. I think though even if this could work, they won't do it for simple monetary reasons. I think there are far more effective treatments for cancer that are pushed behind because A) they're too expensive or B) They don't make enough money. If people didn't care about money we'd be distributing the AIDS medicine freely in Africa and other nations hit by it. I also don't think it's a good idea to get cells to go through cell suicide, it just seems like a pretty bad idea. People have to get sick, people have to have good immune systems, if we don't, then one day something like the common cold will kill us.

    ReplyDelete
  2. Money is the ruler I'm afraid, that egg and bacon sounds tasty.

    ReplyDelete
  3. Money can buy everything, exept a good health, a true friend, a fullfilled life and a honest woman.

    ReplyDelete